Changes

A plan of taking doxycycline (100mg per day) for 2 days before, 7 days during, and 2 days after a high risk trip seems reasonable in terms of reducing a bacterial STI risk, while keeping the duration short enough to limit potential issues like antibiotic resistance. This approach is generally in line with some of the research that's been done on doxycycline as pre- and post-exposure prophylaxis (PEP) for bacterial STIs like chlamydia, gonorrhea, and syphilis, though it’s not universally recommended as standard practice for everyone. Here’s why this might work: