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''During the Trip (7 days):''
This is where you’ll get the bulk of your coverage. A 7-day course during the trip is long enough to help cover multiple exposures, particularly in a high-risk environment like the sex with girls from girlbars you mentionedor GoGos. This is within a reasonable timeframe and should still help reduce the risk of bacterial infections.
''Post-Exposure (2 days after):''
Side Effects: Be mindful of possible side effects like upset stomach, sun sensitivity (make sure to wear sunscreen or protective clothing if you're out in the sun), and potential issues like yeast infections (especially for women, due to changes in the gut flora).
Not 100%: While this approach can lower the risk of bacterial STIs, it doesn’t guarantee complete protection. Condoms will still be your primary method of reducing STI transmission, and taking doxycycline doesn’t fully eliminate the possibility of getting infected. For example, herpes or HPV (human papillomavirus) and HIV are viral infections that doxycycline won’t protect against.
Antibiotic Resistance: A 10-day course is fairly short in terms of antibiotics, and the risk of antibiotic resistance is lower than if you were taking it for months or years. However, avoid using it unnecessarily in the future, as overuse of antibiotics can lead to resistance in the long term.
''A Final Thought:''
This plan seems like a balanced approach, particularly for someone who is aiming to minimize minimise the risk of bacterial STIs without overdoing it on antibiotics. As long as you’re using condoms and keeping other precautions in mind, you’re adding an additional layer of protection, which can help reduce anxiety about exposure.
===Duration===
Doxycycline for STI Prevention (as part of DoxyPrepDoxyPEP):
General Guidance: Unlike malaria prophylaxis, doxycycline for STI prevention typically does not require extended use after the trip ends. Studies and clinical guidelines suggest that you should continue doxycycline for up to 1–2 days after your last potential exposure (i.e., after the last sexual activity that may have been high-risk). The reason for this is that doxycycline works best when taken immediately after exposure, preventing the bacteria (such as chlamydia or gonorrhea) from establishing infection.
